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Choosing the right skincare brand can feel overwhelming, especially if you’re looking for products that are truly effective and backed by scientific research. At Face Dr, our team of Skin Experts has decades of experience guiding clients toward medical-grade, dermatologist-developed skincare. We only work with products we trust and have seen deliver results for real clients, and we’re now able to provide this expert guidance through free online consultations for clients in the US.
Two brands often compared by skincare enthusiasts are ZO Skin Health and SkinMedica. ZO Skin Health is a range we’ve introduced to hundreds of clients over the years, helping them tackle concerns from aging and hyperpigmentation to acne and sensitivity. SkinMedica is another leading medical-grade brand, and many people are curious about how it compares and what sets each apart.
In this article, we’ll break down both brands, highlight their hero products, key benefits, pricing, and more — giving you the information you need to make an informed choice.
Here’s What We’ll Cover in This Article:
- What Is ZO Skin Health?
- What Is SkinMedica?
- What Skin Issues Does ZO Skin Health Tackle?
- What Skin Issues Does SkinMedica Tackle?
- What Skin Type Is ZO Skin Health For?
- What Skin Type Is SkinMedica For?
- What Kind of Products Does ZO Skin Health Have?
- What Kind of Products Does SkinMedica Have?
- Where Can I Buy ZO Skin Health Products?
- Where Can I Buy SkinMedica Products?
- How Much Are ZO Skin Health Products?
- How Much Are SkinMedica Products?
- Summary: Should I Choose ZO Skin Health or SkinMedica?
What Is ZO Skin Health?

ZO Skin Health is a medical-grade skincare brand founded by dermatologist Dr. Zein Obagi. Known for its science-backed formulations and high concentrations of active ingredients, ZO is designed to improve overall skin health and address a wide range of concerns.
The brand follows a simple “Get Skin Ready” philosophy—cleansing, exfoliating, and toning—to prepare the skin for targeted treatments. With decades of research behind its formulations, ZO has earned a reputation among skincare professionals for delivering reliable, visible results while supporting long-term skin health.
What Is SkinMedica?

SkinMedica is a high-end skincare brand founded by dermatologist Dr. Richard Fitzpatrick in 1999 and is part of Allergan Aesthetics, the makers of Botox® and Juvederm®. Known for its science-driven formulations, the brand pioneered Tissue Nutrient Solution (TNS®), a growth factor technology that supports skin renewal and age defense.
With decades of research and clinical studies behind its products, SkinMedica is recognized for its innovative approach and has earned global recognition as a leader in professional skincare.
What Skin Issues Does ZO Skin Health Tackle?
ZO Skin Health is formulated to provide results across a wide range of skin concerns. With high-performance, science-backed ingredients, the brand’s products are designed to help improve skin health, enhance its appearance, and target common and complex issues alike.
Some of the key concerns ZO Skin Health can help address include:
- Persistent acne and breakouts
- Signs of aging, including fine lines and wrinkles
- Uneven skin tone and hyperpigmentation
- Redness and inflammation
- Conditions such as rosacea
- Protection against sun damage
- Maintaining overall skin health and resilience
What Skin Issues Does SkinMedica Tackle?
SkinMedica formulations are designed to support skin renewal, improve texture, and enhance overall radiance. Using innovative ingredients like growth factors, retinol, and hyaluronic acid, the brand provides solutions for a variety of common and advanced concerns.
Some of the main issues SkinMedica products can help with include:
- Signs of aging, including fine lines, wrinkles, and firmness loss
- Uneven skin tone and dark spots
- Dehydration and dullness
- Post-procedure skin recovery and soothing
- Brightening and improving overall skin appearance
What Skin Type Is ZO Skin Health For?

ZO Skin Health has developed a range of products to suit a variety of skin types, making it versatile for different needs. Our Skin Experts often create personalized routines using ZO products because of their flexibility and effectiveness.
Whether your skin is dry, oily, combination, or sensitive, ZO offers solutions to help maintain balance, hydration, and overall skin health. With options tailored to different concerns and textures, the brand provides something for every skin type.
Book your free video consultation with a Skin Expert
What Skin Type Is SkinMedica For?

SkinMedica offers products designed for all skin types, from oily and combination to dry and sensitive. What sets the brand apart is its focus on supporting aging skin, helping to maintain firmness, smoothness, and overall skin health as you get older.
With a variety of textures—from lightweight serums to richer creams—SkinMedica allows you to tailor your routine to your preferences and needs, making it a versatile choice for anyone looking to improve skin appearance and resilience.
What Kind of Products Does ZO Skin Health Have?
ZO Skin Health features a wide range of products, from everyday essentials like cleansers, toners, and sunscreens to targeted treatments for specific concerns. The brand is designed to provide options for different skin types and to complement personalized skincare routines.
Here are some customer favorites:
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Daily Power Defense ($190.00): This lightweight serum is great for daily use. It helps strengthen your skin, boost hydration, and protect against environmental damage. Think of it as an all-in-one step that keeps your skin healthy while tackling early signs of aging. You can explore this product here.

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ZO Gentle Cleanser ($50.00): Perfect for morning and evening, this foaming cleanser removes makeup and impurities without drying out your skin. It’s soothing, gentle, and suitable for all skin types, even sensitive skin, making it an easy addition to any routine. Discover this cleanser here.

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Complexion Renewal Pads ($63.00): These pre-soaked pads are a quick way to gently exfoliate and reduce excess oil. Use them a few times a week to keep pores clear and give your skin a smoother, fresher feel. See more details and purchase here.

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Exfoliating Polish ($68.00): A little goes a long way. This polish uses magnesium crystals to buff away dead skin, leaving your complexion soft and bright. It’s perfect to prep your skin before applying serums or treatments. Explore it here.

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Retinol Skin Brightener (from $117.00): This treatment helps even out skin tone and brighten your complexion. Start with a lower strength if you’re new to retinol and gradually work up to the 1% version for best results. Apply it in the evening, and always follow with sunscreen during the day to protect your skin. Explore the Retinol Skin Brightener range, available in 0.25%, 0.5%, and 1% strengths.

What Kind of Products Does SkinMedica Have?
SkinMedica offers a range of professional-grade products designed to go beyond the basics and help your skin look and feel its best. From everyday essentials like cleansers and moisturizers to treatment serums, eye creams, brighteners, and sunscreens, there’s something for every step of your routine.
Here are some top favorites:
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TNS® Advanced+ Serum ($295.00): This award-winning serum uses growth factors and peptides to help improve firmness and skin texture. Visible results can appear in as little as two weeks, and continued use helps maintain a smoother, healthier complexion. You can explore this product here.

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HA5® Hydra Collagen Replenish + Restore Hydrator ($192.00): A next-generation hydrating serum that delivers up to 48 hours of continuous moisture. It combines five forms of hyaluronic acid, Hydra Collagen, and Advanced VITISENSCE® Technology to instantly plump, smooth, and restore your skin’s hydration reservoir. Discover this product here.

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TNS Eye Repair® ($106.00): Targets the delicate eye area with growth factors and antioxidants to reduce the appearance of fine lines, wrinkles, and dark circles. Apply morning and evening to brighten, hydrate, and smooth. See more about this product here.

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Lumivive® System ($268.00): A two-step day and night system that protects against environmental stressors and supports overnight skin repair. Use the Day Damage Defense Serum in the morning and the Night Revitalize Repair Complex in the evening for a radiant, revitalized look. Check out this product here.

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AHA/BHA Exfoliating Cleanser ($48.00): Gently exfoliates with lactic acid, glycolic acid, and jojoba spheres while cleansing, helping improve skin texture and tone. Use a few times a week to prep your skin for serums and treatments. Get details on this product here.

Where Can I Buy ZO Skin Health Products?
ZO Skin Health products are packed with high-strength, professional-grade ingredients, so they aren’t available to buy online or in high street shops. If you see them being sold without a consultation, they’re likely counterfeit or out-of-date, and won’t give the same results as the real products.
You can get authentic ZO products through approved stockists, including medispas, dermatologists, aesthetic practitioners, and online clinics like Face Dr Our free online consultations let our Skin Experts review your skin, discuss your concerns, and recommend the best products, no pressure to buy.
With Face Dr now available in the US, accessing professional advice and genuine ZO Skin Health products is easier than ever.
Book your free video consultation with a Skin Expert
Where Can I Buy SkinMedica Products?
To ensure you’re getting authentic SkinMedica products, it’s important to purchase from authorized providers or directly through the official SkinMedica website. Using these sources guarantees the products are genuine, properly stored, and effective.
You can easily find an authorized skincare professional by using the Find a Provider tool on the SkinMedica website. This tool helps you locate medispas, dermatologists, and aesthetic clinics near you.
For online purchases, SkinMedica products are available directly at SkinMedica.com, as well as at authorized retailers like Dermstore and LovelySkin. Choosing these channels ensures authenticity and quality.
By choosing authorized channels, you can be confident your SkinMedica products will deliver the results they’re designed for, without the risk of expired or counterfeit items.
How Much Are ZO Skin Health Products?

ZO Skin Health products vary in price depending on what you’re looking for. Their range starts from around $50 for toners and cleansers, up to $200 for some of their advanced serums and targeted treatments.
You can now find full and up-to-date pricing directly on the official ZO Skin Health website or through authorized providers, including dermatologists and aesthetic clinics.
You can also book a free online consultation with one of our Skin Experts. We’ll guide you through the products best suited to your skin, explain how to use them for the best results, and provide pricing.
This approach ensures you know exactly what you’re getting and can choose the products that will be most effective for your skin.
How Much Are SkinMedica Products?

SkinMedica products are generally on the higher end, ranging from around $40 for cleansers up to $300 for advanced serums and targeted treatments.
The pricing reflects the brand’s clinically backed formulations, growth factor technology, and research-driven development. Many users find that SkinMedica products provide noticeable results, making them a worthwhile investment for those seeking effective, professional-grade skincare.
Summary: Should I Choose ZO Skin Health or SkinMedica?
Deciding which brand to try can feel tricky, as each offers unique benefits backed by science. Both ZO Skin Health and SkinMedica are professional-grade skincare brands with products that deliver visible results, but the choice often comes down to your skin type, goals, and preferred treatment approach.
We recommend ZO Skin Health for clients seeking targeted, science-driven solutions for concerns such as acne, uneven tone, or early signs of aging. Our GP-led team has guided thousands of clients using ZO products, ensuring each recommendation is tailored to individual needs. SkinMedica, on the other hand, is a high-end, anti-aging focused brand with potent, research-driven ingredients. Its formulations are designed to support long-term skin renewal and provide intensive results for aging skin.
The most effective way to choose is to speak with a professional. At Face Dr, our Skin Experts have decades of experience and have guided hundreds of clients toward the products that truly work for them. During a free online consultation, they’ll analyze your skin, discuss your concerns and goals, and recommend the brand—and specific products—that suit your needs.
We only ever suggest products and brands we trust, and there’s never any pressure to buy. Whether your priority is gentle daily care or intensive anti-aging treatments, our team can help you make an informed choice and build a routine that works.